Can you disable the notification panel on the Galaxy S22 lock screen?

Unfortunately, you can’t disable the notification/quick settings panel on the Galaxy S22 lock screen at this moment.

But you can tighten the security by ensuring the Lock network and security option to stop anyone from toggling the Wi-Fi, Flight mode, Bluetooth, etc turn on/off on the lock screen.

You can find Lock network and security in Settings > Lock screen > Secure Lock settings